Why Test

Alimetrix® ORAL-Metrix Benefits

Periodontal Disease

Oral health is associated with several other health conditions such as heart disease, diabetes or stroke . Periodontal disease is one of the most common diseases of the oral cavity and a major cause of tooth loss in adults (periodontitis). There are two main categories of periodontal disease in which loss of supporting structures around the tooth occurs: chronic periodontitis and aggressive periodontitis. Chronic periodontitis is the more common of the two, and is a polymicrobial infection. There are five major groups of bacteria associated with the disease progression of chronic periodontitis.

The Alimetrix™ ORAL-Metrix Panel provides a snapshot of the oral microflora, delineating the composition of these microbes in the overall bacterial load. Results are provided in tandem with detected antibiotic resistance markers in a clear concise report that is easily interpretable and most importantly, actionable.

1. American Dental Association

2. Guthmiller JM, Novak KF. Periodontal Diseases. In: Brogden KA, Guthmiller JM, editors. Polymicrobial Diseases. Washington (DC): ASM Press; 2002. Chapter 8.

Alimetrix® ORAL-Metrix Benefits

Cardiovascular Disease

Not only is the mouth an important portal of entry to the digestive tract, but it is increasingly being shown that inflammation and infection of the oral cavity are associated with diseases found in other organ systems, specifically the cardiovascular system. When the integrity of the oral barrier becomes compromised by infection, a gateway is opened for pathogens to access underlying bone and the circulatory system. The acronym HACEK refers to a group of gram-negative bacilli capable of producing endocardial infections. Approximately 10% of endocarditis cases and cardiac valve infections are caused by HACEK bacteria, which originate from the mouth. These organisms are often missed using traditional culture-based diagnostic systems because they are fastidious and slow growing. This in turn leads to uncertainties associated with treatment and questionable outcomes. Alimetrix is able to detect these problematic organisms with exceptional sensitivity and specificity. Our test provides clinicians with clear, actionable information, so they can more effectively treat endocardial infections.

Relevant Diagnostics Empowering Actionable Therapy®